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Ehud Shapiro : ウィキペディア英語版
Ehud Shapiro

Prof. Ehud Shapiro ((ヘブライ語:אהוד שפירא); born 1955) is an Israeli scientist at the Weizmann Institute of Science, where he is a professor in the Departments of Computer Science and Applied Mathematics, and Biological Chemistry.〔http://www.wisdom.weizmann.ac.il/~udi/ Ehud Shapiro at the Weizmann Institute〕
== Education and Professional Background==

Born in Jerusalem in 1955, the guiding light for Ehud Shapiro's scientific endeavors was the philosophy of science of Karl Popper, with which he became acquainted through a high-school project supervised by Moshe Kroy from the Department of Philosophy, Tel Aviv University. Shapiro served in the Israeli Defense Forces from 1973 till 1977 as a tank's crewman, commander and officer, followed by undergraduate studies in Tel Aviv University in Mathematics and Philosophy, completed with distinction in 1979. Shapiro's PhD work with Dana Angluin in Computer Science at Yale university attempted to provide an algorithmic interpretation to Popper's philosophical approach to scientific discovery, resulting in both a computer system for the inference of logical theories from facts and a methodology for program debugging, developed using the programming language Prolog. His thesis, "Algorithmic Program Debugging", was published by MIT Press as a 1982 ACM Distinguished Dissertation, followed in 1986 by "The Art of Prolog", a textbook co-authored with Leon Sterling.
Coming to the Department of Computer Science and Applied Mathematics at the Weizmann Institute of Science in 1982 as a post-doctoral fellow, Shapiro was inspired by the Japanese Fifth Generation Computer Systems project to invent a high-level programming language for parallel and distributed computer systems, named Concurrent Prolog. A two-volume book on Concurrent Prolog and related work was published by MIT Press in 1987. Shapiro's work had a decisive influence on the strategic direction of the Japanese national project, and he cooperated closely with the project throughout its 10-years duration.
In 1993, Shapiro took leave of absence from his tenured position at Weizmann to found Ubique Ltd. (and serve as its CEO), an Israeli Internet software pioneer. Building on Concurrent Prolog, Ubique developed "Virtual Places", a precursor to today's broadly-used Instant Messaging systems. Ubique was sold to America Online in 1995, and following a management buy out in 1997 was sold again to IBM in 1998, where it continues to develop SameTime, IBM's leading Instant Messaging product based on Ubique's technology.
Preparing for return to academia, Shapiro ventured into self-study of molecular biology. Shapiro attempted to build a computer from biological molecules, guided by a vision of "A Doctor in a Cell": A biomolecular computer that operates inside the living body, programmed with medical knowledge to diagnose diseases and produce the requisite drugs. Lacking experience in molecular biology, Shapiro realized his first design for a molecular computer as a LEGO-like mechanical device built using 3D stereolithography, which was patented upon his return to Weizmann in 1998. During the last decade and a half, Shapiro’s lab have designed and successfully implemented various molecular computing devices.
In 2004, Prof. Shapiro also designed an effective method of synthesizing error-free DNA molecules from error-prone building blocks. In 2011, Prof. Shapiro founded the CADMAD consortium: The CADMAD technological platform aims to deliver a revolution in DNA processing analogous to the revolution text editing underwent with the introduction of electronic text editors.
In 2005 Prof. Shapiro presented a vision of the next grand challenge in Human biology: To uncover the Human cell lineage Tree. Inside all of us is a cell lineage tree – the history of how our body grows from a single cell (the fertilized egg) to 100 trillion cells. The biological and biomedical impact of such a success could be of a magnitude similar, if not larger than that of the Human Genome Project. In his TEDxTel-Aviv talk "Uncovering The Human Cell Lineage Tree - The next grand scientific challenge"〔(【引用サイトリンク】title=Ehud Shapiro: Uncovering The Human Cell Lineage Tree )〕 Prof. Shapiro described the system and results obtained with it so far, and a proposal for a FET Flagship project "Human Cell Lineage Flagship initiative"〔(【引用サイトリンク】title=Cell Lineage Project - Homepage )〕 for uncovering the Human cell lineage tree in health and disease.

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